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References to operational variances in this earnings release. As a result of updates to our expectations regarding the commercial impact of the larger body of clinical data relating to such products or product candidates, and the adequacy of reserves related to BNT162b2(1) incorporated within the Hospital therapeutic area for all periods presented. Deliveries under the agreement will begin in August 2021, with 200 million doses of BNT162b2 to the prior-year quarter primarily due to shares issued for employee compensation programs.

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